In August 1861 the London-based newspaper The Times published the world’s first “daily weather forecast.” The term itself was created by the enterprising meteorologist Robert FitzRoy, who wanted to distance his work from astrological “prognostications.” That story has led to a widespread assumption that weather forecasting is an entirely modern phenomenon and that in earlier periods only quackery or folklore-based weather signs were available.
However, more recent research has demonstrated that astronomers and astrologers in the medieval Islamic world drew widely on Greek, Indian, Persian, and Roman knowledge to create a new science termed astrometeorology. Central to the new science was the universal belief that the planets and their movements around Earth affected atmospheric conditions and weather. It was enthusiastically received in Christian Latin Europe and was further developed by Tycho Brahe, Johannes Kepler, and other astronomers. The drive to produce reliable weather forecasts led scientists to believe that astrometeorological forecasting could be more accurate if they used precise observations and records of weather to refine predictions for specific localities. Such records were kept across Europe beginning in the 13th century and were correlated with astronomical data, which paved the way for the data-driven forecasts produced by FitzRoy.1
Islamicate astrometeorologists were the first to replace the ancient practice of observing only short-term signs, such as clouds and the flight of birds, to predict weather. They based their action on the hypothesis that weather is caused by the movements of planets and mediated by regional and seasonal climate conditions. Improved calculations of planetary orbits and updated geographical and meteorological information made the new science possible and compelling.
The prospect of acquiring reliable weather forecasts, closely linked to predictions of coming trends in human health and agricultural production, made the new meteorology attractive in Christian Europe too. Considerable pride shines through medieval Christian accounts of the weather questions that they could now start to answer. Central among them was one that classical meteorologists had failed to figure out: How can weather vary so much from one year to the next when the seasons are caused by regular, repeating patterns produced by Earth’s spherical shape and its interactions with the Sun?
Topics: Asteroids, Biology, Evolution, Existentialism, Research
Note: Working on two reviews, and my research proposal. It’s a very busy writing semester.
Dinosaur and fossil aficionados are intimately familiar with the meteorite strike that drove Tyrannosaurus rex and all nonavian dinosaurs to extinction around 66 million years ago. But it is often overlooked that the impact also wiped out entire ecosystems. A new study shows how those casualties, in turn, led to another particularly profound evolutionary outcome: the emergence of the Amazon rain forest of South America, the most spectacularly diverse environment on the planet. Yet the Amazon’s bounty of tropical species and habitats now face their own existential threat because of unprecedented destruction from human activity, including land clearing for agriculture.
The new study, published on Thursday in Science, analyzed tens of thousands of plant fossils and represents “a fundamental advance in knowledge,” says Peter Wilf, a geoscientist at Pennsylvania State University, who was not involved in the research. “The authors demonstrate that the dinosaur extinction was also a massive reset event for neotropical ecosystems, putting their evolution on an entirely new path leading directly to the extraordinary, diverse, spectacular and gravely threatened rain forests in the region today.”
These insights, Wilf adds, “provide new impetus for the conservation of the living evolutionary heritage in the tropics that supports human life, along with millions of living species.”
Topics: Biology, Chemistry, DNA, Nobel Prize, Research, Women in Science
This year’s (2020) Nobel Prize in Chemistry has been awarded to two scientists who transformed an obscure bacterial immune mechanism, commonly called CRISPR, into a tool that can simply and cheaply edit the genomes of everything from wheat to mosquitoes to humans.
The award went jointly to Emmanuelle Charpentier of the Max Planck Unit for the Science of Pathogens and Jennifer Doudna of the University of California, Berkeley, “for the development of a method for genome editing.” They first showed that CRISPR—which stands for clustered regularly interspaced short palindromic repeats—could edit DNA in an in vitro system in a paper published in the 28 June 2012 issue of Science. Their discovery was rapidly expanded on by many others and soon made CRISPR a common tool in labs around the world. The genome editor spawned industries working on making new medicines, agricultural products, and ways to control pests.
Many scientists anticipated that Feng Zhang of the Broad Institute, who showed 6 months later that CRISPR worked in mammalian cells, would share the prize. The institutions of the three scientists are locked in a fierce patent battle over who deserves the intellectual property rights to CRISPR’s discovery, which some estimate could be worth billions of dollars.
“The ability to cut DNA where you want has revolutionized the life sciences. The genetic scissors were discovered 8 years ago, but have already benefited humankind greatly,” Pernilla Wittung Stafshede, a chemical biologist at the Chalmers University of Technology, said at the prize briefing.
Although scientists were not surprised Doudna and Charpentier won the prize, Charpentier was stunned. “As much as I have been awarded a number of prizes, it’s something you hear, but you don’t completely connect,” she said in a phone call with the Nobel Prize officials. “I was told a number of times that when it happens, you’re very surprised and feel that it’s not real.”
At a press briefing today, Doudna noted she was asleep and missed the initial calls from Sweden, only waking up to answer the phone finally when a Nature reporter called. “She wanted to know if I could comment on the Nobel and I said, Well, who won it? And she was shocked that she was the person to tell me.”
Topics: Civics, Civil Rights, Climate Change, COVID-19, Democracy, Existentialism, Human Rights
Thank you, Reginald!
You’re all signed up for “(1st Dose) COVID – 19 Vaccine Clinic.”
03/11/2021 (Thu.) 1:45pm – 2:00pm EST
Location: NC A&T Alumni Foundation Building (200 N. Benbow Rd.)
My Comment: Older graduate student, 58 years.
Thank you for registering to receive dose 1 of the COVID-19 vaccine. Please note the following:
The instructions noted the address (I knew), where to park in proximity to the NC A&T Alumni Foundation building, instructions to enter the building from N. Benbow Road, and to bring a valid student ID. The same building I’ve celebrated the Greensboro Four every first of February, kicking off African American/Black History Month at the nation’s largest HBCU.
My wife received her first dose of the Pfizer vaccine last Saturday at the Greensboro Coliseum. It’s the ten-year anniversary of the Fukushima Daichi accident. I received my first dose of the Moderna vaccine on also ironically, the first anniversary the World Health Organization declared SARS-CoV-2, the Novel Coronavirus, a worldwide pandemic.
Every STEM major student at a primary or historically black college suddenly was thrust into a world of “I Am Legend” protocols against an invisible zombie apocalypse. Navigating research to attain a Master’s, or Ph.D. is challenging enough: add to it KN95 masks, 3.66 meters of social distance (12 feet, for the British unit crowd), washing hands, hand sanitizers every 10 meters, and protocol-driven digital, and analog sign-in/sign-out for contact tracing. There’s also been isolation, the lack of banter with classmates, no lunches between experiments, or card games. Science is from our hunter-gatherer ancestors: it’s a social exercise. Our worlds have been reduced to the dimensions of our laptop monitors, the visual cues common to hominids in conversation reduced to two-dimensional “Zoom fatigue.”
To cope with the angst of “sameness,” I retreated, or returned more apt and accurately, to spoken word poetry: STEM extended by one vowel is STEAM, the “A” for art, and Einstein played the violin. On Sundays, I perform for a venue in Austin, Texas that’s called “Spoken and Heard,” started by a friend going by the stage name “Element 615” (don’t bother looking it up: it doesn’t exist), managed by some poetry friends, and streamed on Facebook and YouTube via Skype. Our poetry tends to center on the topics of the recent week’s news.
“Mask Mandates and Starships” was my reaction to the day before, the state of Texas lifted their statewide mask mandate. The news for Greg Abbott’s re-election looked grim after botched handling of a once-in-a-hundred-years climate change event (that seems to be occurring annually). If Abbott didn’t learn anything from the last administration when you can’t solve a problem: bluff, blame, and deflect to something else. Gaslighting 101. It solves nothing but shows his disdain for the citizens of Texas: he really thinks they’re stupid. No one rows a boat, or pilots a light sail in multiple directions. It gets you nowhere fast.
The thesis of the piece is, it will take extreme and global cooperation to build ONE vehicle capable of interstellar travel, let alone a fleet of them. The same cooperation we’re going to need to get out of this pandemic. Though there is much writing of papers on the Alcubierre Drive, a breakthrough to superluminal speeds taking us to other worlds is highly unlikely. We’re born, will live, and die on this one. Hopefully, so will our progeny. We still have radiation poisoning, the current, and future pandemics, climate disasters that are occurring with the frequency of subway lines in New York, or Philly. Continuation of any civilization isn’t guaranteed, and discontinuations have many precedents in history.
Zoonotic diseases aren’t new, and they tend to strike every one hundred years. The Great Dying was due to the introduction of things like measles, smallpox, influenza, typhus, and tuberculosis to Native American populations by the invasion of Spain and Portugal to the Americas. It is naïve, and ignorant to name any pathogen after its point of origin; racist and xenophobic to center it on one culture. It is also placing whole populations not responsible for the spread in danger of physical violence, which solves nothing. The first piece of legislation on immigration was the Chinese Exclusion Act of 1882, meant to curb the rise in their population for ten years, signed into law by President Chester A. Arthur on May 6, 1882. This is in America’s DNA. Tribalism and any other narcissistic “ism” will not save us.
Asian Americans scapegoated. Black Lives (obviously don’t) Matter. The LGBT are human beings, not scarecrows hung like Matthew Shepard. “Women’s Rights ARE Human rights.” Unless the pathogen was dropped on us from Alpha Centauri, it, and we all live here.
We either live together or die miserably, and sadly into extinction.
What if this pandemic, / Is Gia’s test / Before we leave the nest? / “In space, no one can hear [you]r screams,” / No matter replicators or Uber Eats, / No 911 to call for assistance, / No tribes to define oneself with, / No conservatives, liberals, republicans, or democrats, / The only question is, “no rescue is coming; can WE fix it?” / No poetic Latin words E Pluribus Unum, / The only governing philosophy boiled down to three letters: GSD, equaling “get shit done!” / More “final frontier” than we’ve ever been,.. from “Mask Mandates and Starships.”
We conclusively know now we cannot gaslight a pandemic. 543,690 deaths, and counting. If we can’t do the simple things, are we mature enough to become a space-faring species?
What if? Are we?
We all know the truth: more connects us than separates us. But in times of crisis, the wise build bridges, while the foolish build barriers. We must find a way to look after one another as if we were one single tribe. Chadwick Boseman, as King T’Challa in the movie, “Black Panther” (Rest In Power), from Internet Movie Database.
Topics: Mars, NASA, Space Exploration, Spaceflight
Data from the powerful science tool includes sounds of its laser zapping a rock in order to test what it’s made of.
The first readings from the SuperCam instrument aboard NASA’s Perseverance rover have arrived on Earth. SuperCam was developed jointly by the Los Alamos National Laboratory (LANL) in New Mexico and a consortium of French research laboratories under the auspices of the Centre National d’Etudes Spatiales (CNES). The instrument delivered data to the French Space Agency’s operations center in Toulouse that includes the first audio of laser zaps on another planet.
“It is amazing to see SuperCam working so well on Mars,” said Roger Wiens, the principal investigator for Perseverance’s SuperCam instrument from Los Alamos National Laboratory in New Mexico. “When we first dreamed up this instrument eight years ago, we worried that we were being way too ambitious. Now it is up there working like a charm.”
Perched atop the rover’s mast, SuperCam’s 12-pound (5.6-kilogram) sensor head can perform five types of analyses to study Mars’ geology and help scientists choose which rocks the rover should sample in its search for signs of ancient microbial life. Since the rover’s Feb. 18 touchdown, the mission has been performing health checks on all of its systems and subsystems. Early data from SuperCam tests – including sounds from the Red Planet – have been intriguing.
“The sounds acquired are remarkable quality says Naomi Murdoch, a research scientist and lecturer at the ISAE-SUPAERO aerospace engineering school in Toulouse. “It’s incredible to think that we’re going to do science with the first sounds ever recorded on the surface of Mars!”
Topics: Biology, DNA, Physics, Polymer Science, Research
DNA molecules are not fixed objects – they are constantly getting broken up and glued back together to adopt new shapes. Davide Michieletto explains how this process can be harnessed to create a new generation of “topologically active” materials.
Call me naïve, but until a few years ago I had never realized you can actually buy DNA. As a physicist, I’d been familiar with DNA as the “molecule of life” – something that carries genetic information and allows complex organisms, such as you and me, to be created. But I was surprised to find that biotech firms purify DNA from viruses and will ship concentrated solutions in the post. In fact, you can just go online and order DNA, which is exactly what I did. Only there was another surprise in store.
When the DNA solution arrived at my lab in Edinburgh, it came in a tube with about half a milligram of DNA per centimeter cube of water. Keen to experiment on it, I tried to pipette some of the solution out, but it didn’t run freely into my plastic tube. Instead, it was all gloopy and resisted the suction of my pipette. I rushed over to a colleague in my lab, eagerly announcing my amazing “discovery”. They just looked at me like I was an idiot. Of course, solutions of DNA are gloopy.
I should have known better. It’s easy to idealize DNA as some kind of magic material, but it’s essentially just a long-chain double-helical polymer consisting of four different types of monomers – the nucleotides A, T, C and G, which stack together into base pairs. And like all polymers at high concentrations, the DNA chains can get entangled. In fact, they get so tied up that a single human cell can have up to 2 m of DNA crammed into an object just 10 μm in size. Scaled up, it’s like storing 20 km of hair-thin wire in a box no bigger than your mobile phone.
A recent genetic association study1 identified a gene cluster on chromosome 3 as a risk locus for respiratory failure after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A separate study (COVID-19 Host Genetics Initiative)2 comprising 3,199 hospitalized patients with coronavirus disease 2019 (COVID-19) and control individuals showed that this cluster is the major genetic risk factor for severe symptoms after SARS-CoV-2 infection and hospitalization. Here we show that the risk is conferred by a genomic segment of around 50 kilobases in size that is inherited from Neanderthals and is carried by around 50% of people in south Asia and around 16% of people in Europe.
The COVID-19 pandemic has caused considerable morbidity and mortality, and has resulted in the death of over a million people to date3. The clinical manifestations of the disease caused by the virus, SARS-CoV-2, vary widely in severity, ranging from no or mild symptoms to rapid progression to respiratory failure4. Early in the pandemic, it became clear that advanced age is a major risk factor, as well as being male and some co-morbidities5. These risk factors, however, do not fully explain why some people have no or mild symptoms whereas others have severe symptoms. Thus, genetic risk factors may have a role in disease progression. A previous study1 identified two genomic regions that are associated with severe COVID-19: one region on chromosome 3, which contains six genes, and one region on chromosome 9 that determines ABO blood groups. Recently, a dataset was released by the COVID-19 Host Genetics Initiative in which the region on chromosome 3 is the only region that is significantly associated with severe COVID-19 at the genome-wide level (Fig. 1a). The risk variant in this region confers an odds ratio for requiring hospitalization of 1.6 (95% confidence interval, 1.42–1.79) (Extended Data Fig. 1).
The genetic variants that are most associated with severe COVID-19 on chromosome 3 (45,859,651–45,909,024 (hg19)) are all in high linkage disequilibrium (LD)—that is, they are all strongly associated with each other in the population (r2 > 0.98)—and span 49.4 thousand bases (kb) (Fig. 1b). This ‘core’ haplotype is furthermore in weaker linkage disequilibrium with longer haplotypes of up to 333.8 kb (r2 > 0.32) (Extended Data Fig. 2). Some such long haplotypes have entered the human population by gene flow from Neanderthals or Denisovans, extinct hominins that contributed genetic variants to the ancestors of present-day humans around 40,000–60,000 years ago6,7. We therefore investigated whether the haplotype may have come from Neanderthals or Denisovans.
Topics: Energy, Materials Science, Nanotechnology, Quantum Mechanics, Solar Power
ABSTRACT Solution-processed colloidal quantum dot (CQD) solar cells are lightweight, flexible, inexpensive, and can be spray-coated on various substrates. However, their power conversion efficiency is still insufficient for commercial applications. To further boost CQD solar cell efficiency, researchers need to better understand and control how charge carriers and excitons transport in CQD thin films, i.e., the CQD solar cell electrical parameters including carrier lifetime, diffusion length, diffusivity, mobility, drift length, trap state density, and doping density. These parameters play key roles in determining CQD thin film thickness and surface passivation ligands in CQD solar cell fabrication processes. To characterize these CQD solar cell parameters, researchers have mostly used transient techniques, such as short-circuit current/open-circuit voltage decay, photoconductance decay, and time-resolved photoluminescence. These transient techniques based on the time-dependent excess carrier density decay generally exhibit an exponential profile, but they differ in the signal collection physics and can only be used in some particular scenarios. Furthermore, photovoltaic characterization techniques are moving from contact to non-contact, from steady-state to dynamic, and from small-spot testing to large-area imaging; what are the challenges, limitations, and prospects? To answer these questions, this Tutorial, in the context of CQD thin film and solar cell characterization, looks at trends in characterization technique development by comparing various conventional techniques in meeting research and/or industrial demands. For a good physical understanding of material properties, the basic physics of CQD materials and devices are reviewed first, followed by a detailed discussion of various characterization techniques and their suitability for CQD photovoltaic devices.
Topics: Civics, Civil Rights, Democratic Republic, Existentialism, Fascism, Human Rights
100 photos, Time: In August 1955, Emmett Till, a black teenager from Chicago, was visiting relatives in Mississippi when he stopped at Bryant’s Grocery and Meat Market. There he encountered Carolyn Bryant, a white woman. Whether Till really flirted with Bryant or whistled at her isn’t known. But what happened four days later is. Bryant’s husband Roy and his half-brother, J.W. Milam, seized the 14-year-old from his great-uncle’s house. The pair then beat Till, shot him, and strung barbed wire and a 75-pound metal fan around his neck, and dumped the lifeless body in the Tallahatchie River. A white jury quickly acquitted the men, with one juror saying it had taken so long only because they had to break to drink some pop. When Till’s mother Mamie came to identify her son, she told the funeral director, “Let the people see what I’ve seen.” She brought him home to Chicago and insisted on an open casket. Tens of thousands filed past Till’s remains, but it was the publication of the searing funeral image in Jet, with a stoic Mamie gazing at her murdered child’s ravaged body, that forced the world to reckon with the brutality of American racism. For almost a century, African Americans were lynched with regularity and impunity. Now, thanks to a mother’s determination to expose the barbarousness of the crime, the public could no longer pretend to ignore what they couldn’t see.
I am a child of “forced bussing,” emphasized by the dominant culture of North Carolina in 1971, when 1954’s Supreme Court Brown vs. Board of Education Decision, and “all deliberate speed” reached my municipality. I remember being nine years old, riding on buses at zero-dark-thirty in the morning to Rural Hall Elementary for the fourth grade, a limited experiment in federally-mandated diversity. I traveled to was in what was then, the rich, white suburbs. Every time my friends and I got off buses, we were miles from our homes.
We generally stayed in clicks: black youths on one side of the cafeteria, white youths on the other. In the evenings, I remember watching local and national news where high school students brought chains, bats, and knives. I recall waiting for our powder keg to explode.
Then, we played a game of football during recess. I don’t know what “did it” for the girls, but boys covered in sweat, mud, and scrapes develop bonds that are hard to ignore. Thankfully, the powder keg never went off.
From Rural Hall, we were bussed back to East Winston-Salem at Fairview Elementary for fifth, and sixth grade. On to Mineral Springs Middle School for seventh, and eighth grade. Atkins, Carver, Hanes, and Paisley – traditionally, African American High Schools that reliably fed HBCUs – were “demoted” to ninth/tenth grade high schools, so that every student in the city would have the “benefit” of diplomas from the traditionally white high schools of North, East, Mount Tabor, and West.
The good news: most of the fourth graders that aged through this forced diversity got used to seeing people other than themselves. Star Trek was in syndication, and we were inspired by the vision of a future that at least our descendants would have their acts together, and learn, like we did to live together post-warp drive, or football.
The not-so-good news: There were quite a few interracial couples, which I had never seen before. Quite a few “Christian” Academies sprung up to sidestep what their parents saw as ungodly miscegenation. I haven’t kept contact with my former classmates from Rural Hall Elementary, Mineral Springs Middle School, Atkins High School, and North Forsyth High School. I can’t help but imagine that many of them on the other side of the cafeteria before our mud-soaked football games have returned to the other side, donned red hats, and QAnon paraphernalia.
There was a list of Emmett Tills before Emmett Till. The brutality visited upon his teenage body compared modernly to Trayvon Martin, Jordan Davis, Renisha McBride, Eric Garner, Sandra Bland, Ahmaud Aubrey, Breonna Taylor, and George Floyd. There are literally hundreds more. Many, like the Emmett Tills before Emmett Till, are unknown, unheard of: unlisted.
The times they want to return to wasn’t so much the president named Eisenhower versus Obama; white picket fences in Levittown’s, or affordable healthcare: “great again” is the ability to reign terror, and murder on an entire community – black, brown, LGBT, women, with absolute impunity. They made that QUITE clear on January 6, 2021.
Every significant group that has had knees on their necks, oppressed by the dominant group since Plymouth Rock took inspiration from the efforts that started post-1865, to this present political darkness. It will continue until E Pluribus Unum isn’t just a quaint Latin phrase. We cannot be a democratic republic, AND a nihilistic, fascist dictatorship.
Their “great again” wish is that Mother Till hadn’t opened that casket.
We are NOT going back! Black lives, and democracy, matter.
Topics: African Americans, Civics, Civil Rights, History, Human Rights
“If you can control a man’s thinking you do not have to worry about his action. When you determine what a man shall think you do not have to concern yourself about what he will do. If you make a man feel that he is inferior, you do not have to compel him to accept an inferior status, for he will seek it himself. If you make a man think that he is justly an outcast, you do not have to order him to the back door. He will go without being told; and if there is no back door, his very nature will demand one.” Dr. Carter Godwin Woodson, The Mis-Education of the Negro
Just before midnight at the close of a hot summer day in 1916, a natural gas pocket exploded 120 feet beneath the waves of Lake Erie. It happened during work on Cleveland’s newest waterworks tunnel, a 10-foot-wide underwater artery designed to pull in water from about five miles out, beyond the city’s polluted shoreline. The blast left twisted conduit pipes littering the tunnel floor and tore up railroad tracks inside the corridor, with noxious smoke curling off the rubble. When the dust settled, 11 tunnel workers were dead.
Two rescue parties entered the tunnel searching for survivors. But they lacked proper safety equipment for the smoke and fumes; 11 of the 18 rescuers died. Some 11 hours later, desperate to save anyone still alive, the Cleveland Police turned to Garrett A. Morgan—a local inventor who called himself “the Black Edison”—and the gas mask he had patented two years earlier.
“He rustled his brother Frank,” says the inventor’s granddaughter, Sandra Morgan. “They threw a bunch of gas masks in the car—remember, they were selling these things—and in their pajamas, drove down to the lakefront.”
Some five years later, in the early 1920s, the inventor witnessed a horrific accident between an automobile and a horse-drawn cart at an intersection. Once again, his ingenuity kicked in. Before Morgan, traffic signals only had two positions: stop and go. “My grandfather’s great improvement,” Sandra says, “was the ‘all hold’—what is now the amber light.” Morgan patented the three-position traffic signal in 1923 and soon sold the idea to General Electric for $40,000 (the equivalent of about $610,000 today). He purchased 250 acres later that year in Wakeman, Ohio, and transformed it into an African American country club complete with a party room and dance hall.
“The mere imparting of information is not education. ” Dr. Carter G. Woodson